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Company Overview

We are developing safer, less expensive CAR-T products which can target more cancers and save more lives. We do this using our integrated model which drives the development of our products through preclinical testing to the clinic. Our mission is to develop and commercialize innovative cell-based products and to treat disease, improve patient health and Quality of Life.

TC BioPharm is a privately-held, clinical-stage cell therapy company developing advanced allogeneic CAR-T cell therapy products for the treatment of cancer. Established in 2014, we have expanded into 5 global locations and have grown to over 100 employees.

History

  • Feb 2014

    TCB was founded

    TCB commenced operations in February 2014, leasing space for its lab, office and cleanroom facilities in April 2014. The initial build was completed within 6 months.

  • Jan 2015

    TC BioPharm received MHRA approval to initiate cancer trial

    TC BioPharm received a license from MHRA to produce gamma delta T cell therapy products at its clinical manufacturing facility near Glasgow, UK.

  • Jul 2015

    TC BioPharm raised £1.2 million for UK cancer trial

    TC BioPharm raised equity and grant funding from Scottish Enterprise and Investing Woman.

  • Dec 2015

    Initiation of ImmuniCell® trial

    This was an adaptive clinical trial for TC BioPharm’s autologous gamma delta T cell product for melanoma, lung and kidney cancer.

  • Jan 2017

    TC BioPharm raised £6.25 million

    Funds raised from NIPRO and Scottish Investment Bank for further clinical development of gamma delta T cell therapies.

  • Aug 2017

    TC BioPharm granted €4 million from EU H2020 research and innovation program

    The funding supported development of TC BioPharm’s clinical program of unmodified allogeneic gamma delta T cell products for the treatment of cancer in a phase 1 clinical trial.

  • Sep 2017

    TC BioPharm licensed CAR-T technology from UCL

    The agreement was to progress innovative gene-modified T cell therapies capable of treating childhood and adult cancers of the blood such as acute myeloid leukemia (AML).

  • Dec 2017

    TC BioPharm partnered with bluebird bio

    The companies continue to work together to advance TC BioPharm’s lead CAR-engineered gamma delta T cell program into clinical trials as well as on additional hematologic and solid tumor targets.

  • Feb 2018

    TC BioPharm partnered with NIPRO

    The strategic partnership co-develops a novel gamma delta CAR-T product for the treatment of cancer.

  • Feb 2018

    TC BioPharm opened first overseas office in Japan

    TC BioPharm opened the new office as a foundation to expand its cell therapy business through Japan and Asia.

  • May 2018

    TC BioPharm partnered with Scotia Biologics

    Using Scotia’s unique technology, the two companies are working on a range of cancer-targeting single-chain antibodies, each of which can be formulated to treat a specific type of cancer.

  • Jan 2019

    TC BioPharm created allogeneic cell banks for CAR-T

    Via funding from H2020, TC BioPharm completes formulation of its first allogeneic gamma delta T cell bank.

  • Feb 2019

    Strategic partnership established with Trinity College Dublin

    The partnership with Dublin’s Trinity College was established for in-house production of V delta 1 gamma delta T cell banks for treatment of solid tumors.

  • Mar 2019

    TC BioPharm extended space at Glasgow headquarters

    TC BioPharm used the new space to facilitate manufacturing of GMP lentivirus, a key starting material in the process for creating their pioneering CAR-T cancer therapies.

  • Apr 2019

    Initiated phase 1 allogeneic gamma delta T cell trial

    The trial, for treatment of patients suffering from Acute Myeloid Leukemia (AML), is being conducted at the Institute of Hematology and Blood Transfusion (ÚHKT) in Prague, Czech Republic.

  • May 2019

    TC BioPharm opened offices in London and Leiden

    Continued growth saw TC BioPharm expand office space in London, UK and Leiden, The Netherlands.