Current Vacancies

Development Manager (Cellular Immunology)

OVERALL ROLE OBJECTIVE

The post-holder will provide leadership to the Cellular Immunology teams, with responsibility for coordinating our fundamental immunology and infectious disease programmes. The post-holder will develop projects to establish a role for gdT in infection and lead our anti-viral CAR-T program through to clinical trials. Additional responsibilities for this role will include extensive drug product characterisation across our gamma delta T cell platform, working with the Process Development team to continually drive improvements to the manufacturing process underpinned by scientific principles.

 

The Development Manager will join TCB, an emerging cancer immunotherapy company developing cell-based treatments for cancer and severe viral infections. Based at their manufacturing facility in the central belt of Scotland, the successful candidate will report directly to the Senior Product Development Manager.  TCB is a fast-growing immunotherapy company developing cell-based treatments for cancer patients; moreover, our unique culture, values and working environment attracts, retains, and inspires people to give their best.

 

RESPONSIBILITIES INCLUDE BUT ARE NOT LIMITED TO:

  • Coordinating programmes to generate data on fundamental gamma delta T cell biology, with a view to using these learnings to deliver improvements to TCB's clinical products.
  • Establishing TCB's anti-infection programme to develop allogeneic and CAR products for viral and pathogenic targets.
  • Managing supervisors, scientists and technicians across multidisciplinary teams.
  • Training and supervising both experienced and inexperienced members of staff as appropriate, so that technical knowledge and competence is communicated effectively.
  • Coordinating the planning, execution and analysis of scientific investigations and studies.
  • Working internally & externally to identify new opportunities for continual improvement.
  • Being able to organize, interpret, and present results to external collaborators.
  • Being responsible for the preparation of documentation, including Development Plans and Reports and SOPs.
  • Ensuring that work is performed in accordance with the Company’s Quality Assurance and Health and Safety policies including the provision of COSHH/BIOCOSHH/Risk assessments.
  • Working collaboratively across multiple functions and projects.
  • Contributing to a dynamic, exciting culture which embraces teamwork and innovation.

 

QUALIFICATIONS

  • Degree qualified, with a PhD in a life sciences related subject. These qualifications are essential pre-requisites for this role.

 

SKILLS & EXPERIENCE

  • A strong background in leading R&D programmes in cellular immunology, with at least 5 years of relevant post-doctoral experience in either an academic or industrial setting and evidence of successful delivery is essential.
  • A good awareness of cell & gene therapies, including an understanding of the progression of candidate products from lab bench to clinical trial is essential.
  • Previous management/supervisory experience is essential.
  • Extensive experience in working with human immune cells, ideally in combination with viral or parasite co-infection models.
  • Significant experience in cell culture and cell-based assays, with the ability to provide technical expertise to team projects.
  • Awareness of of GMP regulations surrounding ATMPs.
  • Experience in preparing written documentation, including SOPs, Development Reports & Change Controls.
  • Excellent written/oral communication and interpersonal skills.
  • Excellent Microsoft Office skills.
  • Thorough approach and high attention to detail.
  • Strong time management and organisational skills.

 

If you are looking to work within a challenging, dynamic, and rewarding environment, then TCB represents an excellent career move. This is an opportunity to be part of a growing, ambitious business where people development is critical to future success. As we continue to expand, there will be career opportunities on a truly global scale.

 

TCB is an Equal Opportunity Employer. We welcome and encourage diversity in the workplace.

 

Together with a competitive salary, we offer a comprehensive range of benefits and an excellent working environment.

 

Office based.

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